Brandon Aiyuk suffered a torn ACL, MCL, and possibly more damage to his knee, ending his season just weeks after signing a major contract.
Deebo Samuel was hospitalized with pneumonia after struggling to breathe during the game, indicating severe impact on the 49ers' receiving lineup.
Both quarterbacks, Brock Purdy and Patrick Mahomes, delivered the worst passer ratings of their careers in a matchup that didn't live up to expectations.
With significant injuries plaguing the team and reduced personnel, the 49ers struggled offensively, highlighting the challenges of competing against Kansas City's defense.
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