Brock Purdy's performance will be crucial as the 49ers look to exploit the Chiefs' defensive weaknesses, especially with key players like L'Jarius Sneed missing.
George Kittle's ability to capitalize on Kansas City's weak pass coverage by linebackers will be vital for the 49ers' offensive success.
Deebo Samuel's expected performance includes more targets than in the last Super Bowl, aligning with hopes for a more dynamic role.
Nick Bosa is anticipated to disrupt the game significantly, building on a strong performance marked by 14 pressures against the Seahawks.
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