Head coach Kyle Shanahan has officially ruled out running back Isaac Guerendo for Sunday’s game against the Miami Dolphins due to a hamstring injury sustained in Week 15.
Defensive end Nick Bosa, who recently returned after missing three games, is once again dealing with hip and oblique issues, making him a questionable participant this week.
Linebacker Dre Greenlaw, after missing the previous 13 games, is now battling Achilles and knee issues, raising concerns as the 49ers head into a critical matchup.
Despite the injury challenges, defensive tackle Maliek Collins returned as a full participant in practice and will contribute to the team without any limitations.
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