The Brazil forward opened the scoring with a lovely finish from 20 yards.
Real Madrid, who welcomed back England midfielder Jude Bellingham from suspension, are eight points clear of Barcelona at the top of La Liga with eight games remaining.
Real host Manchester City in the quarter-final first leg of the Champions League on 9 April (20:00).
The record 14-time European champions are in Manchester for the return leg on 17 April (20:00).
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