"The Study Goals The Alzheimer's Association and the National Institute on Aging completed an ambitious research endeavor: the US POINTER Trial (U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk). The goal: To find a constellation of effective lifestyle changes to combat cognitive impairment and dementia. It involved a herculean effort. Scholars at five research sites recruited over 2,000 adults aged 60 to 79 who were at risk of cognitive impairments. Participants engaged in the study interventions for two years."
"My prior blog posts addressed whether you have dementia, how lifelong factors may protect against dementia, and the role of genetics in dementia. But everyone wants to know, "What can I do to prevent dementia right now?" A caveat: Check with a healthcare provider before you make lifestyle changes. An online blog educates the public about new research but not what is right for you."
The US POINTER Trial enrolled over 2,000 adults aged 60 to 79 at increased risk of cognitive impairment. Participants were largely sedentary, consumed poor diets, and had at least two vascular or demographic risk factors such as family history, hypertension, dyslipidemia, prediabetes, or high-risk demographic status. The randomized controlled trial compared an intensive, multi-domain lifestyle intervention to a control condition over two years. The intervention targeted diet, physical activity, sleep, stress reduction, social engagement, and cardiovascular risk management. Results indicated that coordinated, sustained lifestyle changes can reduce dementia risk and may reverse some late-life cognitive decline. Healthcare consultation is recommended before changing behaviors.
Read at Psychology Today
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