Air pollution linked to lung cancer-driving DNA mutations, study finds
Briefly

A study indicates that air pollution is linked to significant DNA mutations driving lung cancer in never-smokers. Researchers analyzed lung tumors from 871 patients globally and found a correlation between high air pollution levels and increased cancer-promoting mutations. Notably, fine-particulate air pollution was linked to mutations in the TP53 gene, commonly associated with smoking. Additionally, greater air pollution exposure resulted in shorter telomeres, indicating accelerated aging. As smoking declines, an increasing number of lung cancer cases are identified in never-smokers, particularly in adenocarcinoma forms, highlighting a pressing public health issue.
"Air pollution has been linked to a swathe of lung cancer-driving DNA mutations, in a study of people diagnosed with the disease despite never having smoked tobacco."
"The higher the levels of air pollution in a region, the more cancer-driving and cancer-promoting mutations were present in residents' tumours."
Read at www.theguardian.com
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