Every second, millions of biochemical reactions occur in our cells, notably involving the addition and removal of small carbon molecules from proteins and DNA, which are vital for cellular functions.
Histone modifications, particularly of acetyl and methyl groups, have traditionally been associated with gene regulation, but accumulating evidence indicates these modifications also play crucial roles in cellular metabolism.
Recent studies demonstrate that while histone modifications impact gene activity in some genomic regions, in many others, they do not, indicating their functions may extend beyond gene regulation.
Histones serve as a 'bank' for acetyl groups, enabling cells to manage small carbon molecules necessary for various biochemical reactions, thereby highlighting their role in cellular metabolism.
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