Current research indicates the existence of trillions of bacteriophages within the human microbiome, sparking interest in their potential to impact human health positively. As noted by Breck Duerkop, there's a significant diversity of these phages, and understanding their roles could lead to medical advancements.
Paul Bollyky highlights the complexity of phage interactions with bacteria, acknowledging that the gut hosts both beneficial and harmful phages. Identifying the right phages could enable personalized medical strategies to improve health outcomes.
Colin Hill emphasizes the extraordinary variety of phages present in the gut microbiome, stating the Gut Phage Database as a mere starting point, with only 140,000 identified, suggesting countless unidentified phages likely play crucial roles.
Scientists utilize genetic sequencing of human fecal samples to uncover these phages. The discovery of crAssphage exemplifies the innovative techniques being used to enhance our understanding of microbiome diversity and complexity.
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