"Tests on 39 different tumour types from nearly 15,000 UK patients revealed more than one in six cancers had extrachromosomal DNA, or ecDNA, which can make tumours harder to treat."
"These are the patients who are really suffering because they are not responding to our current therapies and their tumours are so aggressive," said Professor Paul Mischel.
"The analysis cast light on how ecDNA drives cancer growth and resistance, which led researchers to identify a new drug that can selectively destroy affected cells."
"Researchers found that 17.1% of the tumours studied contained ecDNA, especially in forms of breast, brain and lung cancer, affecting a lot of patients worldwide."
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