Over 70% of individuals with severe depression experience anhedonia, a symptom that is extremely challenging to treat and often neglected in current therapies.
The study indicates that a specific brain circuit can either foster resilience against stress or promote vulnerability, impacting the capability to experience pleasure.
Mice under stress displayed a preference for plain water over sugar water, which the researchers interpreted as anhedonia, indicative of their loss of pleasure.
The findings from this research reveal a new potential pathway for treating anhedonia, a condition that affects enjoyment and pleasure in various mental health disorders.
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