These groundbreaking findings advance our understanding of where, how, and when genetic risk contributes to mental disorders such as schizophrenia, post-traumatic stress disorder, and depression...will help researchers pinpoint genetic variants that are likely to play a causal role in mental illnesses and identify potential molecular targets for new therapeutics.
The research is published across 15 papers... reporting findings on population-level analyses linking genetic variants, regulatory elements, and gene expression to regulatory networks, single-cell-level maps of the prefrontal cortex, and experimental analyses validating regulatory elements and genetic variants.
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