Within two weeks, 50% of the pain was gone. And by the end of 10 weeks, he had regained range of motion and the pain was completely gone.
At low doses, rapamycin seems to help tamp down inflammation by inhibiting the mTOR signaling pathway, a key regulator of lifespan and aging.
Physicians prescribe rapamycin off-label for anti-aging purposes, with anecdotes of benefits from about 300 patients. However, research is necessary to understand its actual risks and benefits.
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