The technique harnesses the natural ability of mobile genetic sequences, called jumping genes, to insert themselves into genomes, guided by an RNA molecule termed 'bridge' or 'seekRNA.' It allows editing genes in bacteria and test-tube reactions, potentially revolutionary if adapted for human cells for large DNA segment modifications.
Unlike CRISPR, which primarily alters small genome segments, this molecular oddity offers a unique approach by enabling large-scale genetic modifications without DNA breaks. Sandro Fernandes Ataide highlights its potential as a game-changer in gene editing, opening up a new domain.
Collection
[
|
...
]