The hiPSC-CM models don't perfectly match an adult cardiomyocyte...we were really interested in what we could do to make these cardiomyocytes match an adult cardiomyocyte as much as possible.
In the study, Burridge and his collaborators cultured hiPSC-CMs and performed high-throughput assays to measure maturation of the cells...they found several factors could indicate when the cells are mature.
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