Researchers at Harvard Medical School have identified a unique population of regulatory T cells (Tregs) in the brains of healthy mice, challenging their traditional role in immune regulation. These Tregs not only prevent inflammation but also support nerve cell renewal, particularly in memory-related areas. Published in Science Immunology, this groundbreaking work suggests that if these findings are confirmed in further studies, it could lead to innovative therapies for neurodegenerative diseases, highlighting the intricate role of Tregs as protectors of brain health.
"We found a thus-far-uncharacterized, unique compartment of regulatory T cells residing in the meninges surrounding the brain and involved in an array of protective functions."
"The work adds to a growing body of research showing that Tregs go above and beyond their traditional immune-regulatory duties and act as tissue-specific guardians of health."
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