Daily briefing: Why the man behind a 'mouse utopia' disappeared from the scientific literature
Briefly

In villages in Honduras, where interactions are mainly face to face and people have minimal exposure to antibiotics and processed foods, those living in the same house share up to almost 14% of the microbial strains in their guts. Interestingly, those who don't live together but regularly see one another share 10%. This shows a fascinating link between social interactions and microbial diversity, indicating that our social connections could impact our gut health.
The recent approval of KarXT, known commercially as Cobenfy, marks a significant shift in psychiatric treatment, targeting muscarinic receptors in the brain. This innovative approach could not only pave the way for treating schizophrenia but also has potential applications for psychosis related to Alzheimer's disease, tapping into the complexities of cognitive function and antipsychotic capabilities. Its active ingredient's interaction with M1 and M4 receptors points to a promising future in psychiatric medicine.
The notion that friends influence each other's gut microbiome is both intriguing and revealing. It suggests that our health may be more interconnected than previously acknowledged. The results indicate that social contacts extend beyond mere emotional support; they might also play a crucial role in shaping our biological makeup. By understanding how our microbial communities are influenced by the people we choose to surround ourselves with, we can grasp the broader implications of our social choices on our health.
Read at Nature
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