We’re very excited to see what people do with this," says John Jumper, who leads the AlphaFold team at DeepMind and last month, along with CEO Demis Hassabis, won a share of the 2024 Chemistry Nobel Prize for their work on the AI tool.
Crucially, the AlphaFold3 server prevented scientists from predicting how proteins behave in the presence of potential drugs. But now, DeepMind's decision to release the code means academic scientists can predict such interactions by running the model themselves.
DeepMind initially said that making AlphaFold3 available only through a web server struck the right balance between enabling access for research and protecting commercial ambitions.
The publication of AlphaFold3 without its code or model weights drew criticism from scientists, who said the move undermined reproducibility. DeepMind swiftly reversed course and said it would make an open-source version of the tool available within half a year.
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