A landmark genome-wide study has identified nearly 300 gene locations and 36 unique genes associated with bipolar disorder, emphasizing genetic diversity across various ancestries. Researchers from different backgrounds collaborated to analyze a vast number of participants, making it the largest study to date. The findings suggest a complex genetic architecture underlying bipolar disorder and propose avenues for more personalized treatments. Evidence shows that current knowledge of genetic risk factors can be expanded beyond previous studies focused mainly on individuals of European ancestry, thus enhancing understanding of bipolar disorder across diverse populations.
The study identified nearly 300 gene locations and 36 unique genes most likely to be linked to bipolar disorder. This enlarges the identified genetic risk factors for the disorder significantly.
The research highlights the genetic diversity of bipolar disorder, revealing that genes contributing to specific disorder subtypes differed among individuals of various ancestries.
#bipolar-disorder #genetics #nih-research #personalized-medicine #nih-funded-study #psychiatric-genomics-consortium
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