The article explores the critical role of gut microbes in the efficacy and dosage of psychoactive drugs. It highlights that these microbes can enhance, degrade, or modify medication, causing variability in treatment effectiveness among individuals. For instance, drugs like Prozac and L-DOPA are affected by gut microbes, making precise dosing challenging. Additionally, the gut microbiome can produce its own psychoactive substances like serotonin and dopamine. Individual differences in microbial makeup can alter treatment responses, emphasizing the importance of balancing the microbiome through diet to improve psychiatric medication outcomes.
"Psychoactive drugs taken orally must pass a gauntlet of gut microbes, which can affect the dosage and efficacy of psychiatric medications."
"Gut microbes can produce psychoactive substances like serotonin and dopamine, impacting mental health treatments and complicating medication effectiveness."
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