"It's chaotic at the two ends of a woman's reproductive years," MacGregor says, emphasizing the hormonal fluctuations during puberty and menopause significantly increase migraine susceptibility for women.
"Despite various treatment options, migraines remain the leading cause of disability-adjusted life years (DALYs) for women aged 15 to 49," highlighting the severe impact of migraines on women's daily lives and health.
"Women suffer from migraines three times as often as men, with episodes that are more prolonged and intense," illustrating the gender disparity in migraine prevalence and severity.
"A sudden drop in estradiol...is thought to play a key role in menstrual migraines," explaining the hormonal connection that influences the frequency and intensity of migraines in women.
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