"The finding emerged from a major study that combined 11 brain-imaging datasets from around the world in an effort to build a reliable picture of how the substances temporarily rewire the brain."
"All five drugs dissolve the common order, the usual hierarchy of brain systems. They flatten the hierarchy and that probably underlies what some people describe as this raw access to one's own consciousness."
"While there were some differences in how the drugs changed brain activity, there was substantial overlap in their impact on how regions of the brain communicated with one another."
"Scientists have long sought to understand how psychedelics work in the brain to produce hallucinations and what some describe as the dissolution of the self, when people feel their sense of identity disintegrate."
A major study identified a hallmark signature of psychedelic drugs in the human brain, revealing a shared impact among LSD, psilocybin, DMT, mescaline, and ayahuasca. Researchers analyzed over 500 brain scans from 267 individuals across five countries, finding that these substances dissolve the usual hierarchy of brain systems, enhancing communication between brain regions. This research is significant as it supports the potential therapeutic use of psychedelics for severe mental health conditions, including depression and PTSD, by providing insights into their effects on brain function.
Read at www.theguardian.com
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