Hyperemesis gravidarum (HG) affects 2% of pregnancies, leading to severe dehydration and malnourishment; geneticist Marlena Fejzo's experience sparked research on the condition's cause.
Fejzo's 2023 study identified high GDF15 levels during pregnancy contributing to HG symptoms, proposing interventions targeting hormone levels to alleviate the condition's debilitating effects.
After struggling with funding rejections for years, Fejzo collaborated with 23andMe to find a gene linked to HG, demonstrating that persistent research efforts can eventually lead to breakthrough discoveries.
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