Symptoms after vaccination were somewhat more frequent in the [lupus] patients than in the normal subjects, they reported... No significant induction or increase of pre-existing autoantibodies among the patients was detected after vaccination.
When experts have gone looking for evidence that vaccines lead to flares among people with systemic lupus erythematosus (SLE), they've usually found that a small minority of patients experience an uptick in disease activity, but that uptick tends to be mild or moderate.
What the data suggests is that most people do well, and severe flares are very uncommon... Most have found some evidence that, yes, heightened disease activity or symptomatology can occur following a vaccine, but this happens in a minority of patients and tends not to be severe.
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