A significant study published in Nature Medicine analyzed the health benefits of GLP-1 receptor agonists like Ozempic and Wegovy in diabetes patients over 3.5 years. The research revealed improvements in numerous health issues beyond weight and blood sugar management, including addictions, Alzheimer's disease, and psychotic disorders. Notably, 13% of those with addiction issues saw improvements, and there was an 18% reduction in psychotic disorder risk. This comprehensive investigation highlights the potential of these drugs in addressing various conditions linked to brain function and impulse control.
"Interestingly, GLP-1RA drugs act on receptors that are expressed in brain areas involved in impulse control, reward and addiction - potentially explaining their effectiveness in curbing appetite and addiction disorders."
"In particular, Al-Aly said that the drugs' impact on addiction disorders 'stood out' to him, with 13 percent of the GLP-1 cohort who had issues with addiction seeing improvement."
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