Creatine is a naturally occurring compound stored in muscle and liver that replenishes adenosine triphosphate (ATP) via the phosphocreatine system to maintain cellular energy. During short, high-intensity activity creatine donates phosphate groups to regenerate ATP, supporting muscle contraction and energy stability in tissues including the brain. Dietary intake (red meat, fish) and endogenous synthesis determine individual creatine levels, which commonly sit around 60–80%, prompting supplementation to restore reserves. Higher creatine availability increases ATP for intense workloads, improving physical performance and enabling researchers to observe cognition-related benefits from supplementation. Supplementation thus targets both athletic and cognitive outcomes by supporting energy-demanding brain processes.
Creatine can make you smarter. It's basically an established fact now that creatine supplementation will increase your strength, aid in building bigger muscles, and improve your all-around performance. But creatine has been found to provide benefits for much more than just athletics and looks. Recently, one of the more interesting areas of research has focused on creatine's role in cognition and whether supplementation can improve it. Here's what you need to know about taking creatine for your cognition.
Creatine is a naturally occurring compound stored within the body's muscles and liver. Its primary physiological role is to maintain energy availability by replenishing adenosine triphosphate (ATP) through the phosphocreatine system (one of your three metabolic systems). During short bursts of high-intensity activity, creatine rapidly donates a phosphate group to regenerate ATP, the body's immediate energy currency. This buffering system supports muscle contraction, cellular energy stability, and proper function of energy-demanding tissues like the brain.
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