Discovery of Proteins and Metabolites Implicated in Mental Illness and Neurodevelopmental Disorders
Briefly

from National Institute of Mental Health (NIMH)1 month ago
The NIMH PsychENCODE Consortium has produced vital resources revealing gene expression and regulation in the human brain, yet understanding signaling pathways in mental illness remains limited.
National Institute of Mental Health (NIMH)https://www.nimh.nih.gov/funding/grant-writing-and-application-process/concept-clearances/2024/discovery-of-proteins-and-metabolites-implicated-in-mental-illness-and-neurodevelopmental-disorders
To fully understand the biological pathways affected by mental illness, it is crucial to study protein expression, modifications, and interactions, rather than relying solely on genomic data.
National Institute of Mental Health (NIMH)https://www.nimh.nih.gov/funding/grant-writing-and-application-process/concept-clearances/2024/discovery-of-proteins-and-metabolites-implicated-in-mental-illness-and-neurodevelopmental-disorders
Current limitations in correlating mRNA expression with protein levels impede our ability to predict the signaling pathways that are key to mental health issues.
National Institute of Mental Health (NIMH)https://www.nimh.nih.gov/funding/grant-writing-and-application-process/concept-clearances/2024/discovery-of-proteins-and-metabolites-implicated-in-mental-illness-and-neurodevelopmental-disorders
Despite the significance of proteins and metabolites in cellular function, the exploration of their roles in mental illness presents a largely unexplored area in psychiatric research.
National Institute of Mental Health (NIMH)https://www.nimh.nih.gov/funding/grant-writing-and-application-process/concept-clearances/2024/discovery-of-proteins-and-metabolites-implicated-in-mental-illness-and-neurodevelopmental-disorders
Read at National Institute of Mental Health (NIMH)
#neuroscience #mental-illness #proteomics #research #psychencode-consortium
[
|
]