"Joseph Bass, MD, PhD, the Charles F. Kettering Professor of Medicine, has been elected to the National Academy of Medicine ( NAM) for his foundational work in expanding the field of circadian mechanisms in metabolic health and disease. NAM is one of three academies that make up the National Academies of Sciences, Engineering, and Medicine in the United States. Membership in the academy is considered one of the highest honors in science and medicine."
"In a landmark paper published in Science in 2005, Bass' laboratory established the key role of circadian clocks in regulating metabolism at the molecular and cellular levels. This work catalyzed additional research investigating circadian dysregulation on metabolic health and disease, including a recent study led by Bass and published in Science, which found that energy release during meals is a key molecular mechanism through which internal clocks control energy balance."
Joseph Bass is the Charles F. Kettering Professor of Medicine, chief of Endocrinology, Metabolism and Molecular Medicine, and director of the Center for Diabetes and Metabolism. He was elected to the National Academy of Medicine for foundational work expanding circadian mechanisms in metabolic health and disease. Bass discovered that clock gene mutations contribute to obesity, beta-cell failure and metabolic syndrome, reshaping understanding of circadian control of energy balance and conditions tied to shift work, sleep loss and night eating. His research established molecular roles for circadian clocks in metabolism and identified meal energy release as a mechanism linking internal clocks to energy balance, with implications for timing of eating, weight gain, diabetes risk, dieting approaches, sleep loss, and nutritional care for critically ill patients. His work also revealed transcription factors that influence insulin-producing beta-cell identity and function.
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