
"Scientists at Washington University School of Medicine in St. Louis have uncovered a new way that brown fat, a type of fat that burns energy, can boost the body's metabolism. This process allows cells to consume more fuel and generate heat, improving overall metabolic health. Conducted in mice, the research points to new possibilities for using brown fat to address metabolic conditions such as insulin resistance and obesity."
"Brown fat is unique because it turns energy (calories) from food into heat. Unlike white fat, which stores energy, or muscle, which uses it immediately, brown fat helps keep the body warm in cold environments. Exposure to cold can increase the amount of brown fat, and scientists have long suggested that activating it could support weight loss by increasing calorie burning."
A hidden backup heat-producing mechanism exists in brown fat that enables cells to consume more fuel and generate heat even when usual energy systems slow. This secondary pathway increases resting energy expenditure and can raise overall metabolic rate. The mechanism was identified in studies conducted in mice and is distinct from mitochondrial thermogenesis. Activating this backup heater could support weight loss or weight control by increasing energy wastage, potentially offering safer or easier metabolic interventions. The pathway presents opportunities to target energy expenditure to address metabolic conditions including insulin resistance and obesity.
Read at ScienceDaily
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