The 49ers face significant challenges with key players like Christian McCaffrey and Deebo Samuel out, while the Rams are missing star wideouts Cooper Kupp and Puka Nacua.
Both teams may depend heavily on their running game due to injuries to prominent pass-catchers, potentially leading to a run-heavy approach during the divisional clash.
With both defenses likely focusing on the ground game, expect players like Jordan Mason for the 49ers and Kyren Williams for the Rams to have increased roles.
Nick Bosa and Charvarius Ward's active status offers the 49ers a defensive boost, but how the missing offensive stars will impact game dynamics remains crucial.
Collection
[
|
...
]