A study published in Nature Partner Journals' Aging found psilocybin, the psychoactive compound in psychedelic mushrooms, can slow aging in human cells and extend lifespan in mice. Human lung and skin cells treated with psilocin exhibited significant increases in lifespan, with lung cells showing a 29% boost and up to 57% with higher doses. In mice, those given psilocybin lived 30% longer than controls, demonstrating improved health markers. The study indicates the potential of psilocybin in longevity research and its broader implications in mental health treatment.
When dosing older mice with psilocybin and comparing them to a control group, the research team found the aged mice lived 30% longer than their peers who weren't subject to the same psychedelic journey.
Exposure to the psychedelic reduced the oxidative stress that can lead to cell damage and preserved the length of telomeres, a part of the chromosome implicated in cancer and other age-related diseases.
Human fetal lung cells treated with psilocin showed a 29% boost to their cellular lifespans - a number that rocketed to 57% when exposed to a much larger dosage.
Psilocybin is an emerging frontier in mental health research, but it obviously holds some strong potential in the field of longevity too.
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