"A 2026 paper published online in Aging reported that theobromine (a naturally occurring alkaloid derived from cocoa) is associated with slower epigenetic aging in humans. Researchers from King's College London analyzed data from two European cohorts comprising 2,600+ participants to examine the circulating blood levels of theobromine. Higher levels of theobromine were associated with reduced epigenetic age acceleration (slower aging)."
"Theobromine, found in abundance in dark chocolate, is significantly associated with slower epigenetic aging. Dark chocolate, particularly varieties with 70 percent or higher cocoa, contains substantially higher levels of theobromine, and higher theobromine levels were linked to a younger biological age. At the same time, my colleagues and I continue to study chocolate as a potent drug-like activator of brain reward circuitry. People who are "chocoholics" may eat too much chocolate. Or want to."
Higher circulating theobromine levels correlate with reduced epigenetic age acceleration in over 2,600 European participants. Theobromine is abundant in dark chocolate, especially varieties with 70% or greater cocoa, linking higher consumption to younger biological age. Epigenetic age measures molecular cell aging independent of chronological age; accelerated epigenetic aging associates with greater risk of age-related disease and mortality. Chocolate contains phytochemicals that can improve blood flow, reduce inflammation, and influence cellular signaling. Chocolate also activates brain reward circuitry, which can drive strong cravings and potentially excessive consumption despite potential health-related effects.
Read at Psychology Today
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