The Red Devils, under Erik ten Hag, are looking to improve significantly this season after a strong backing in the summer, creating immense pressure for a good start.
Marco Silva's side, who triumphed at Old Trafford last season, enters the match with confidence and aims to make a meaningful statement on the opening day.
For UK viewers, the match will be broadcast live on Sky Sports Main Event and Sky Sports Premier League, with coverage beginning at 7pm BST.
Fans can also tune in to the live action through the Sky Go app, while Standard Sport will provide a live blog for uninterrupted matchday coverage.
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