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Luton is in good form and has a clinical edge in the final third. They are unbeaten in their previous six appearances and have scored 12 goals in their last four matches.
Last seen snatching a remarkable 4-4 stalemate away at Newcastle, the former Watford boss should find the mood in his camp at a red-hot high.
Sheffield United is struggling at the bottom of the Premier League table and has suffered heavy defeats in recent matches. They have lost all three of their previous meetings against Premier League opposition and are 10 points adrift of safety.
Last seen putting in a nightmare display at Bramall Lane as they were eventually hit with a 5-0 drumming at the hands of Aston Villa, Chris Wilder has an almighty job on his hands.