The research delves into a single-cell transcriptomic atlas of over 2.3 million cells from 17 tissues in mice, investigating sex and androgen effects on molecular programs and populations. Notably, androgens influence sex-biased immune gene expression and cell types like group 2 innate lymphoid cells.
By integrating data with the UK Biobank, the study uncovers potential disease targets and risk gene enrichment related to sex-biased diseases, suggesting the androgen pathway as a promising therapeutic target.
[
Collection
]
[
|
...
]