Formation of memory assemblies through the DNA-sensing TLR9 pathway - Nature

Here we explored whether an overarching process could integrate stimulus-dependent and pre-existing mechanisms that underlie the commitment of neurons to memory-specific assemblies.

To this end, we performed bulk RNA-sequencing of total RNA isolated from individual mouse hippocampi obtained either 96 h or 21 days after contextual fear conditioning (CFC) and noted a robust difference in the gene expression profiles.

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