Cortical computation depends on excitatory and inhibitory neuron assemblies in canonical microcircuits. The synaptic innervation of PV interneurons is crucial for cortical stability and plasticity during development and in the adult brain.
Regulation of PV interneuron recruitment and excitability is essential for maintaining the excitation-inhibition balance in cortical circuits, impacting learning processes. However, molecular mechanisms like BMP signalling underlying these functions are poorly understood.
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