In vitro reconstitution of epigenetic reprogramming in the human germ lineEstablishing a robust strategy for inducing epigenetic reprogramming and differentiation of human pluripotent stem cell-derived germ cells is a fundamental challenge.
Control of neuronal excitation-inhibition balance by BMP-SMAD1 signalling - NatureNeuronal circuits in the neocortex rely on key parameters like the synaptic innervation of inhibitory PV interneurons to control stability and plasticity.