The Dallas Cowboys will be challenged without leading rusher Rico Dowdle due to illness, leaving Ezekiel Elliott and Dalvin Cook as lead backs against a strong San Francisco defense.
The Cowboys face mounting injuries, missing four starters, including key defensive players Micah Parsons and DeMarcus Lawrence, as they struggle with the NFL's worst-ranked run offense.
Ezekiel Elliott's performance has diminished significantly after a decent start, and with Dalvin Cook yet to make an impact this season, the Cowboys' run game is under pressure.
Dowdle's absence impacts an already struggling Dallas Cowboys run game, averaging only 77.2 yards per game, raising concerns ahead of their matchup with the formidable 49ers.
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