The odyssey of three women and BO-112, the molecule that tricks cancer
Briefly

Juana Santiago's journey with metastatic melanoma began when her daughter noticed unusual spots on her scalp. Despite attempts with Nivolumab and numerous surgeries, her condition worsened. By 2025, however, she found herself cancer-free thanks to a significant discovery in cancer research. Biologist Marisol Soengas noted the alarming increase in melanoma cases due to unsafe tanning practices. In Spain, melanoma incidences had risen substantially, while the World Health Organization projected a dramatic increase in mortality associated with it by 2040. Melanoma originates in melanocytes, the pigment-producing cells of the skin.
Nivolumab, a drug that has saved hundreds of thousands of lives, wasn't working for Juana Santiago, even after 15 surgeries and a massive skin graft.
Melanoma was once rare, but the tanning trend has caused cases to skyrocket, especially among fair-skinned individuals. In Spain, incidence rose from 12 to 15 per 100,000 people.
Biologist Marisol Soengas highlights the rise of melanoma due to unsafe tanning practices, warning that brown skin is a response to damage.
The World Health Organization anticipates nearly 100,000 melanoma deaths worldwide by 2040, representing a 70% increase from current figures.
Read at english.elpais.com
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