#melanoma

#melanoma

The ability of cancer cells to adopt new phenotypes without further DNA mutations is now well understood to substantially influence tumour behaviour. Such plasticity has long been observed in melanoma, where early studies identified transcriptomic and phenotypic states not linked to specific genetic lesions1. More recent evidence indicates that most tumours encompass a heterogeneous yet reproducible number of transcriptional states3,4. The extent to which tumour cells transition between states is an open area of investigation and has been hypothesized to be regulated by cues from the tumour microenvironment (TME).

No matter how high or how far, he made a way. Not only did he make my dreams come true, he chased them with me. Worldwide he was there, my biggest cheerleader. He is my best friend, my voice of reason, and my favorite phone call every day.

The new melanoma center at Maimonides Health integrates services from dermatology, pathology, surgery, and cancer treatment, streamlining care for melanoma patients.

While this may not be the best direction to be heading with my changes, amazingly (to me), I still seem keen to keep living, loving and having fun, whenever possible.

The proposed BayesPPDSurv method allows for accurate coefficient estimation and reliability in power and type I error rate calculations for time-to-event data in clinical trials.