World's First "Biological Computer" Runs AI Models On Actual Human Brain Cells - Yanko Design
Briefly

The CL1, developed by Cortical Labs, is the world's first biological computer powered by living human neurons. Displayed at MWC 2025, it combines biological intelligence with silicon technology to adapt and learn similarly to human brains. Utilizing Synthetic Biological Intelligence (SBI), the CL1 allows neurons to strengthen or weaken connections, enabling real-time data processing. This technology has transformative potential, particularly in drug discovery, offering quicker insights into treatments for Alzheimer’s and Parkinson’s due to its organic adaptability.
The CL1 combines human neurons with silicon hardware, allowing it to process information biologically, adjust dynamically, and learn without massive datasets, revolutionizing AI.
Cortical Labs’ CL1 represents a leap in technology, where human cognition and machine efficiency merge to create a powerful biological computer that adapts in real-time.
The ability of CL1 to strengthen or weaken connections as it learns could transform fields like drug discovery, speeding up advancements in treating neurological diseases.
Unlike traditional AI, CL1’s neurons adapt organically, eliminating the need for pre-programmed rules, which marks a significant shift in how we understand and utilize AI.
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