A study published in JAMA Network Open has found that upper gastrointestinal (GI) damage has an association with a 75% greater risk of a future diagnosis of Parkinson's disease.
Despite the substantial numbers of people living with Parkinson's disease, the cause remains unclear; however, significant research has pointed towards gut-related factors.
The research team defined mucosal damage as erosions, ulcers, or acid-induced injuries, which were thoroughly examined through upper GI endoscopy.
This ongoing investigation into the 'gut-first' hypothesis suggests that Parkinson's disease may begin within the gut and progress through the nervous system to the brain.
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