'Remarkable' new cat cancer genome could benefit humans
Cats and humans develop similar cancers due to shared tumor-causing genetic mutations, suggesting cats could improve cancer research and treatments for both species.
Sperm donor with rare cancer mutation fathered nearly 200 children in Europe
A sperm donor carrying a germline TP53 mutation has fathered at least 197 children across 14 European countries, placing many offspring at high cancer risk.
Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors - Nature
Disrupting the cyclin A–E2F1 interaction selectively induces apoptosis in RB1/TP53-deficient small cell lung cancer, offering a synthetic lethal therapeutic strategy.