fromwww.nature.com
6 days agoHow short peptides disassemble tau fibrils in Alzheimer's disease
Reducing fibrous aggregates of the protein tau is a possible strategy for halting the progression of Alzheimer's disease (AD). The D-peptide D-TLKIVWC disassembles ultra-stable tau fibrils extracted from autopsied brains of individuals with AD into benign segments without any energy source except ambient thermal agitation.
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