Substrate recognition and cleavage mechanism of the monkeypox protease, Core protease
The structure of CorePro from poxviruses, crucial for viral maturation, has been determined, providing a target for potential antiviral drug development.
Author Correction: Structure of the human dopamine transporter in complex with cocaine
In the version of this article initially published, the r.m.s.d. values for the hDAT structure compared to dDAT and hSERT were corrected for accuracy, with original values being 1.8 A and 13.0 A.
Structures and mechanism of human mitochondrial pyruvate carrier
The study unveils six different cryo-EM structures of the human mitochondrial pyruvate carrier (MPC) showcasing its mechanisms in transporting pyruvate for cellular metabolism.
Microsoft Releases BioEmu-1: A Deep Learning Model for Protein Structure Prediction
BioEmu-1 revolutionizes protein structure prediction by generating ensembles rather than static models, enhancing understanding in drug development and biology.
Structural dynamics of human fatty acid synthase in the condensing cycle
FASN dynamics during fatty acid synthesis involve unsynchronized reactions and do not require large rotational movements between its functional domains.