Microsoft Releases BioEmu-1: A Deep Learning Model for Protein Structure PredictionBioEmu-1 revolutionizes protein structure prediction by generating ensembles rather than static models, enhancing understanding in drug development and biology.
Structural dynamics of human fatty acid synthase in the condensing cycleFASN dynamics during fatty acid synthesis involve unsynchronized reactions and do not require large rotational movements between its functional domains.
Google DeepMind's new AI can model DNA, RNA, and 'all life's molecules'AlphaFold 3 predicts structures of all life's molecules using AI; significant improvement in accuracy
The conformational space of RNase P RNA in solution - NatureRNA conformational dynamics are crucial for various cellular functions and can inform drug discovery.
Google DeepMind's new AI can model DNA, RNA, and 'all life's molecules'AlphaFold 3 predicts structures of all life's molecules using AI; significant improvement in accuracy
The conformational space of RNase P RNA in solution - NatureRNA conformational dynamics are crucial for various cellular functions and can inform drug discovery.
The structure of apolipoprotein B100 from human low-density lipoprotein - NatureApolipoprotein B100's structure was resolved in unprecedented detail, enhancing understanding of LDL's role in atherosclerosis and potential therapeutic avenues.
Birth of protein folds and functions in the virome - NatureViral proteins possess critical functions, yet many remain poorly understood due to high divergence and lack of annotated homologues.
Bridging structural and cell biology with cryo-electron microscopy - NatureCryo-EM has revolutionized the study of large, functional complexes in structural biology.The interplay between cryo-EM and cryo-electron tomography shows promise in visualizing macromolecules in their natural context.