#structural-biology

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#alphafold2 #protein-structure-prediction #fertilization-proteins #protein-folding #open-source-ai #openfold3
fromNature
2 days ago

AlphaFold is five years old - these charts show how it revolutionized science

Five years ago, in late November 2020, researchers at London-based Google DeepMind unveiled AlphaFold2. The artificial intelligence tool for predicting protein structures generated stunningly accurate 3D models that, in some cases, were indistinguishable from experimental maps, dominating a long-running structure-prediction challenge. The first version of AlphaFold was announced in 2018, but its predictions weren't nearly as good as its successor, which limited its impact.
Artificial intelligence
Artificial intelligence
fromNature
1 month ago

Open-source protein structure AI aims to match AlphaFold

OpenFold3 is an open-source AI model that predicts protein 3D structures and interactions and aims to approach AlphaFold3 performance while being freely available to researchers and companies.
fromCornell Chronicle
2 months ago

Nozomi Ando named to Schmidt Polymaths cohort | Cornell Chronicle

remarkable track records, promising futures and a desire to expand their research portfolios by exploring a substantive disciplinary or methodological shift soon after achieving tenure,
Science
fromwww.nature.com
7 months ago

Substrate recognition and cleavage mechanism of the monkeypox protease, Core protease

The structure of CorePro from poxviruses, crucial for viral maturation, has been determined, providing a target for potential antiviral drug development.
Data science
fromwww.nature.com
7 months ago

Author Correction: Structure of the human dopamine transporter in complex with cocaine

Corrections made to the structure analysis of hDAT with no impact on overall conclusions.
OMG science
fromWIRED
7 months ago

'We Are Not Programmed to Die,' Says Nobel Laureate Venki Ramakrishnan

Ramakrishnan defines death as the loss of coherent function despite many living cells.
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