#organoid-models

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#neuroendocrine-prostate-cancer #nsd2 #h3k36me2 #lineage-plasticity #placental-organoids #stem-cells #hcg
Medicine
fromNature
2 days ago

NSD2 targeting reverses plasticity and drug resistance in prostate cancer - Nature

NSD2-mediated H3K36me2 drives neuroendocrine lineage plasticity and castration-resistant prostate cancer; NSD2 inhibition reverses neuroendocrine differentiation in organoid models.
fromwww.nature.com
2 months ago

Lab-Made Mini Organs Could Transform Female Reproductive Medicine

We must do a pregnancy test on them, Moffett said. If Turco was correct, the miniature ball of cells she had created would secrete HCG, the hormone that triggers a positive pregnancy test. I took the stick, put it in, and it was positive, says Turco, now a reproductive biologist at the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland. It was the best celebration.
Science
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