#nih-restructuring

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Non-profit organizations
fromNature
1 day ago

Massive budget cuts for US science proposed again by Trump administration

Proposed budget cuts for major US science agencies include over 50% reductions for NSF and EPA, while military funding increases significantly.
#fda
Public health
fromArs Technica
3 days ago

RFK Jr. wants Americans to use peptides that were banned over safety risks

FDA is considering lifting restrictions on peptides despite safety concerns and lack of evidence for their efficacy.
Healthcare
fromIntelligencer
3 days ago

Casey Means May Be Too Kooky Even for Republicans

The U.S. has been without a surgeon general since January, with Dr. Casey Means' nomination stalled in the Senate.
fromBoston.com
3 days ago

How one family's bipolar disorder experience led to more than $1 billion for the Broad Institute in Cambridge

The Stanley Family Foundation announced another $280 million for the Stanley Center for Psychiatric Research at Broad Institute earlier this month, bringing its total contributions to the Massachusetts-based nonprofit over $1 billion.
Medicine
fromNature
5 days ago

Now is the time for scientific societies to guide global research

Modern scientific societies are increasingly vulnerable due to their dependence on membership fees and journal subscriptions, which are being challenged by the rise of virtual networking and open-access publishing.
Science
#nih-funding
Science
fromNature
2 weeks ago

Daily briefing: Funding calls plummet as NIH turns away from agency-directed science

The NIH shifts funding strategy toward unsolicited research proposals driven by individual scientists' interests rather than addressing specific scientific problems.
Data science
fromNational Institute of Mental Health (NIMH)
4 weeks ago

BRAIN Initiative: Data Archives for the BRAIN Initiative

The BRAIN Initiative data ecosystem provides domain-specific archives for long-term storage, curation, and community access to neuroscience research data, with continued funding essential for maintaining reproducible pipelines and accommodating exponential data growth.
Coronavirus
fromArs Technica
3 weeks ago

NIH director launches "Scientific Freedom" lectures with non-scientist

NIH Director Jay Bhattacharya launched 'Scientific Freedom Lectures' featuring a journalist with fringe COVID and climate views, prioritizing his personal censorship grievances over scientific rigor.
fromwww.scientificamerican.com
2 weeks ago

Influential vaccine advisory panel may be disbanded' after lawsuit, says former vice chair

For more than half a century, the Advisory Committee on Immunization Practices (ACIP) has informed U.S. public health policy, helping to set the country's recommended routine childhood and adult vaccine schedules. In a social media post on Thursday, Malone said that the Trump administration had made the decision to disband and recreate a new ACIP committee.
Public health
fromNextgov.com
3 weeks ago

Tech bills of the week: Improved biological data for research; Section 702 reform; and more

Ushering in the Golden Age of Innovation is about more than just winning the global tech race - it's about securing the safety and prosperity of our country for generations to come. Our bill is an important step in this effort and will better ensure the United States has the infrastructure in place to lead the 21st century.
EU data protection
Non-profit organizations
fromNature
2 weeks ago

NIH pivots away from agency-directed science

The NIH is shifting from solicited grants addressing agency-identified priorities to unsolicited grants driven by individual researchers' interests, reducing administrative costs but potentially limiting large collaborative projects and understudied research areas.
fromMail Online
3 weeks ago

Outrage as cancer-fighting drug in US patent echoes hidden CIA file

According to the patent, a specific crystalline form of the drug known as polymorph C may be more effective than other versions because it is absorbed more efficiently by the body. The patent also notes that laboratory studies showed the drug reduced tumor growth and helped mice with brain tumors live longer, prompting early clinical trials to test whether the treatment is safe and effective in humans.
Cancer
Healthcare
fromNextgov.com
3 weeks ago

AI 'nihilism' is a barrier to better health care, CMS lead says

AI can transform U.S. healthcare delivery, but patient distrust remains the primary barrier requiring clinicians to communicate its life-saving benefits and improved access to care.
Cancer
fromMail Online
3 weeks ago

CIA backlash after hidden document hints at possible cancer cure

A declassified 1951 CIA document summarizes Soviet research identifying biochemical similarities between parasitic worms and cancerous tumors, suggesting potential shared treatment approaches.
fromArs Technica
3 weeks ago

Trump's divisive FDA vaccine regulator self-destructs, will exit agency (again)

Prasad's tenure was generally marked by controversy, but he is departing amid a cluster of self-destructive decisions. Those include a shocking rejection of an mRNA vaccine (which was over the objections of agency scientists and quickly reversed); a demand for an additional clinical trial on a gene therapy for Huntington's disease, which was widely seen as moving the goalpost for the therapy; his startling choice to publicly attack the maker of that gene therapy, UniQure; and alleged abuse of FDA staff, who say he created a toxic work environment.
Medicine
Science
fromNature
3 weeks ago

How data can help to guide NIH funding policy

NIH funding distribution data reveals Massachusetts has slightly higher grant success rates than Iowa and Nebraska, but differences are not statistically significant in available SBIR/STTR datasets.
#research-funding
fromNature
1 month ago
Fundraising

The funding system needs fixing - but it's not a 'waste of time and money'

fromNature
1 month ago
Fundraising

The funding system needs fixing - but it's not a 'waste of time and money'

Non-profit organizations
fromNature
3 weeks ago

How Congress can restore the independence of US science

US federal science governance is shifting from merit-based civil service implementation to presidential political control, threatening research effectiveness and the science base.
Healthcare
fromFast Company
4 weeks ago

Responsible compounding could close the innovation gap

Compounding can responsibly accelerate patient access to needed therapies when grounded in rigorous data, filling genuine clinical gaps while pursuing FDA approval, particularly in underserved areas like women's health.
Public health
fromwww.scientificamerican.com
4 weeks ago

Americans trust federal scientists more than RFK, Jr., poll suggests

Americans trust federal health agency scientists more than Trump administration-appointed leaders, with independent medical organizations like the AAP commanding significantly higher vaccine confidence than the CDC.
fromBoston.com
4 weeks ago

'My scientific career is essentially over.' A brain drain imperils Massachusetts' biomedical future.

Over two-thirds said they recommend their students consider careers outside academia. The majority had delayed hiring in their labs, and one-third had laid off workers. More than one in six said they have lost researchers to institutions in other countries since Trump took office. Sixty-eight percent said funding cuts and federal policy changes had moderately or significantly reduced the scope of their work.
Science
#fda-drug-approval-process
fromFuturism
1 month ago
Healthcare

Government Handing Out Cash Bonuses to Drug Researchers Who Rush Through Regulatory Approvals

fromFortune
4 weeks ago
Public health

'Usually everybody loves money': Trump's FDA chief to start giving bonuses for faster drug reviews | Fortune

Healthcare
fromFuturism
1 month ago

Government Handing Out Cash Bonuses to Drug Researchers Who Rush Through Regulatory Approvals

The FDA introduced a cash bonus program for drug reviewers who complete work ahead of schedule, creating potential conflicts of interest with accelerated approval processes.
fromFortune
4 weeks ago
Public health

'Usually everybody loves money': Trump's FDA chief to start giving bonuses for faster drug reviews | Fortune

#nih
Medicine
fromenglish.elpais.com
1 month ago

The very long road from a cancer cure' in mice to one in humans

Promising mouse cancer cures often fail to become safe, effective human drugs; premature media claims can create false patient expectations and hinder responsible research progress.
fromInside Higher Ed | Higher Education News, Events and Jobs
1 month ago

NSF Plans to Boost Staffing, Halve Grant Solicitations

The fewer solicitations you have, the less time grant applicants have to figure out which of our pigeonholes they fit into. In the past, a solicitation might have been for an individual program, which means it's attached to an individual program officer and a specific dollar amount. Now, instead of going to one program officer's area, the NSF will use technology to better route applications to wherever within the agency they can best be reviewed.
Science
Cancer
fromenglish.elpais.com
1 month ago

Douglas Hanahan, biologist: We don't necessarily need a cure, what we really need is cancer without disease'

Cancer cells acquire hallmarks: uncontrolled proliferation, evasion of growth barriers, resistance to programmed death, and relative immortality, driving tumor diversity and treatment variability.
Public health
fromLGBTQ Nation
1 month ago

Funding cuts are devastating Black HIV prevention work. But activists say pressure is working. - LGBTQ Nation

Federal funding cuts to HIV prevention and care programs threaten Black-led organizations that have historically filled gaps in public health infrastructure and served as first responders to the HIV crisis.
fromNature
1 month ago

The age of animal experiments is waning. Where will science go next?

Last November, the UK government announced a bold plan to phase out animal testing in some areas of research. Animal tests for skin irritation are scheduled for elimination this year, and some studies on dogs should be slashed by 2030. The long-term vision is 'a world where the use of animals in science is eliminated in all but exceptional circumstances'.
Science
fromNature
1 month ago

AI help in grant proposals tied to higher funding odds at NIH

Scientists are increasingly turning to artificial-intelligence systems for help drafting the grant proposals that fund their careers, but preliminary data indicate that these tools might be pulling the focus of research towards safe, less-innovative ideas. These data provide evidence that AI-assisted proposals submitted to the US National Institutes of Health (NIH) are consistently less distinct from previous research than ones written without the use of AI - and are also slightly more likely to be funded.
Artificial intelligence
Higher education
fromNature
2 months ago

'Every aspect of my work life has changed' - scientists reflect on a year of Trump

Executive orders and funding changes during Trump's first year intensified campus censorship, worsened higher-education inequity, and risked access for low-income and LGBTQ+ students.
#hiv
OMG science
fromHarvard Gazette
2 months ago

Why did that cancer cell become drug-resistant? - Harvard Gazette

TimeVault records and stores cellular gene-expression history inside living cells, enabling retrieval of past gene-activity information to study differentiation, stress responses, adaptation, and drug resistance.
Environment
fromNature
2 months ago

Funding cuts could put research into emerging threats to lung health at risk

Closure of the EPA's UNC Human Studies Facility ends a unique human-exposure research capacity crucial for assessing air-quality standards and respiratory health.
#nih-policy
fromNature
1 month ago
Medicine

NIH rolls back red tape on some experiments - spurring excitement and concern

fromNature
1 month ago
Medicine

NIH rolls back red tape on some experiments - spurring excitement and concern

fromArs Technica
1 month ago

NIH head, still angry about COVID, wants a second scientific revolution

At the end of January, Washington, DC, saw an extremely unusual event. The MAHA Institute, which was set up to advocate for some of the most profoundly unscientific ideas of our time, hosted leaders of the best-funded scientific organization on the planet, the National Institutes of Health. Instead of a hostile reception, however, Jay Bhattacharya, the head of the NIH, was greeted as a hero by the audience, receiving a partial standing ovation when he rose to speak.
US politics
#nih-leadership
fromTruthout
1 month ago

Trump Admin Has Made Future of Federal Funding for Cancer Research Uncertain

Brugge and her research team have analyzed the cell structure of more than 100 samples. Using high-powered microscopes and complex computer algorithms, they diagram each stage in the development of breast cancer: from the first sign of cell mutation to the formation of tiny clusters, well before they are large enough to be considered tumors. Their quest is to prevent breast cancer, a disease that afflicts roughly 1 in 8 U.S. women over their lifetimes, as well as some men.
Cancer
Public health
fromwww.theguardian.com
1 month ago

Experts warn NIH director now leading CDC will push RFK Jr's agenda'

Jay Bhattacharya was named acting CDC director while retaining NIH directorship, consolidating power among a small group and raising concerns about vaccine policy.
fromHarvard Gazette
2 months ago

Real-world answers for patients running out of time - Harvard Gazette

But these studies typically require large numbers of patients, huge amounts of data, and thorough follow-ups, none of which comes easy or free. The upshot is fewer investigations into scenarios that are clinically important but unlikely to yield a profit for the firms funding them. Accordingly, researchers have been developing an option that uses real-world data from insurers to save patients from falling through the cracks.
Medicine
Public health
fromwww.scientificamerican.com
1 month ago

Key NIH research institute told to remove references to 'pandemic preparedness'

NIAID staff were ordered to remove 'biodefense' and 'pandemic preparedness' from web pages as the institute shifts focus away from those research priorities.
Science
fromFlowingData
2 months ago

Cuts to science and research in the U.S. over the past year

Administration cuts to science funding, grant withholding, and elimination of research jobs caused a sharp decline in government science agency staffing.
Science
fromNature
1 month ago

Now is not the time to defund human fetal tissue research

Restricting federal funding for human fetal tissue research will impede development of replacement technologies and slow discovery of new medicines.
Science
fromNature
1 month ago

Epstein files reveal deeper ties to scientists than previously known

Jeffrey Epstein had extensive, previously underreported ties to the scientific community, investing and socializing with numerous researchers, revealed by millions of newly released investigative files.
US politics
fromArs Technica
2 months ago

Appeals court upholds block on one of Trump's cuts to research funds

Retroactive reduction of university indirect cost rates to 15% would impose serious financial harm and conflicts with Congress’s budget rider prohibiting such NIH overhead changes.
Science
fromNature
1 month ago

Science funding needs fixing - but not through chaotic reforms

UK research funding is shifting to a top-down, industrially aligned model, creating uncertainty and risking harm to curiosity-driven science, small groups, and future leaders.
Public health
fromArs Technica
1 month ago

Trump official overruled FDA scientists to reject Moderna's flu shot

FDA leadership under Dr. Prasad has issued surprise rejections, creating regulatory unpredictability that raises industry investment and innovation fears and spurred internal complaints.
fromBig Think
2 months ago

The four paths forward for US scientists in 2026

For nearly 100 years, the United States has been the world's leader in a wide variety of scientific fields. No other country has: invested as much in fundamental scientific research, has made more scientific breakthroughs and scientific advances, has attracted more scientific researchers to move there to conduct their research, or has conducted more projects and been home to more scientists that have won Nobel Prizes.
Science
Public health
fromwww.scientificamerican.com
1 month ago

Top medical groups join forces to review vaccine science as CDC faces criticism

The American Medical Association and the Vaccine Integrity Project will independently review vaccine safety and effectiveness to provide evidence-based guidance to doctors and families.
fromJezebel
2 months ago

You've Never Been More Likely to Get Cancer, Survive Cancer, or Be Bankrupted by Cancer

We're living in a curious moment for the status of cancer diagnosis and treatment, within the United States. The overall rate of prevalence for diseases that fall under the wide, wide title of "cancers" is increasing. At the same time, steady improvement to the standard of care and treatment, and newer breakthroughs in therapeutics, have raised survival rates higher than they've ever been before. But for all too many patients, the question is whether they'll be able to afford those
Public health
Public health
fromFuturism
2 months ago

Trump Administration Cancels Grotesquely Unethical Medical Study After Being Caught Red Handed

A proposed HHS-funded randomized trial would have withheld hepatitis B vaccine from 7,000 Guinea-Bissau newborns, raising severe ethical concerns and prompting cancellation.
fromwww.bbc.com
2 months ago

Trial launched to 'help spot health risks early'

Public health consultant Dr Ross Keat said supporting people earlier to make small preventative changes would make "a big difference later on". Some 3,500 people in the north of the island within that age bracket are eligible for the checks. The checks will be carried out by two pre-existing nurses that support GP staff and would not replace GP appointments, Keat explained, adding that the cost would be minimal and absorbed by Ramsey Group Practice.
Public health
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