#neural-tube-defects

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fromIndependent
1 week ago

'It will be life-changing': Screening for two devastating genetic disorders in newborns to begin today

The heel prick test will now be accompanied by testing for spinal muscular atrophy (SMA), a rare muscle-wasting condition that can potentially lead to a child's death by the age of two.
Medicine
fromNature
1 week ago

Single-cell spatiotemporal dissection of the human maternal-fetal interface - Nature

The human maternal-fetal interface (MFI) is a transient hemi-allogeneic amalgam in which maternal decidual stromal cells (DSCs) support placental attachment, recruit immune cells and create a tolerogenic milieu for patterning fetal cytotrophoblast invasion.
Medicine
Health
fromenglish.elpais.com
3 weeks ago

A healthy pregnancy doesn't depend solely on the woman: why the father's health is crucial for child development

Father's health and behaviors significantly impact pregnancy outcomes and child development, challenging the traditional focus solely on the mother.
fromSlate Magazine
3 weeks ago

The Baby's Heart Stopped. One Phrase Has Stuck With Me for Years Since.

There is a piece of advice given to doctors in moments like this: Check your own pulse. Each person in the room has a role, and we perform it best with steady hands and measured voices.
Medicine
Public health
fromwww.theguardian.com
1 month ago

Fetuses likely have more forever chemicals' in blood than thought report

Fetuses contain 42 different PFAS compounds in umbilical cord blood, far exceeding previous estimates based on testing only four common compounds.
Medicine
fromwww.bbc.com
4 weeks ago

Scotland becomes first in UK to test newborns for rare genetic condition

Scotland is the first UK region to test newborns for Spinal Muscular Atrophy, enabling early treatment to improve life expectancy.
UK news
fromwww.bbc.com
2 months ago

Newborn baby dies after mum not woken for heart rate check

Hospital failure to perform required observations and delayed emergency Caesarean led to newborn Sonny Taylor suffering severe brain injury and dying three days later.
fromNews Center
2 months ago

First-Of-Its-Kind Probe Monitors Fetal Health in Utero During Surgery - News Center

The soft, flexible, robotic probe could dramatically improve safety during fetal surgeries, procedures in which physicians operate on a fetus before birth. Currently, doctors primarily rely on intermittent measurements of fetal heart rate using ultrasound imaging from outside the pregnant person's body. The new device, on the other hand, can be gently inserted through the same narrow port already used in fetal surgeries.
Healthcare
Public health
fromNature
2 months ago

Is paracetamol in pregnancy a risk factor for ADHD?

Prenatal paracetamol (acetaminophen) exposure is associated with increased risks of ADHD and other neurodevelopmental disorders in children, and usage during pregnancy is widespread.
fromwww.npr.org
2 months ago

Can leucovorin treat autism? History says, probably not

At a press conference in late 2025, federal officials made some big claims about leucovorin, a prescription drug usually reserved for people on cancer chemotherapy. "We're going to change the label to make it available [to children with autism spectrum disorder]," said Dr. Marty Makary, commissioner of the Food and Drug Administration. "Hundreds of thousands of kids, in my opinion, will benefit." The FDA still hasn't made that label change. Since Makary's remarks, though, more than 25,000 people have joined a Facebook group called Leucovorin for Autism. Most members appear to be parents seeking the drug for their autistic children.
US news
Public health
fromwww.scientificamerican.com
1 month ago

Tylenol orders in pregnant people plummeted after Trump falsely linked the medicine to autism

Trump administration's unsupported claims about acetaminophen causing autism led to a 20% decrease in pregnant patients using the medication and a 71% increase in children prescribed unproven leucovorin treatment.
Medicine
fromNature
1 month ago

World-first stem-cell therapy shows promise for treating spina bifida in the womb

Placenta-derived stem cells applied to exposed fetal spinal cords during in utero surgery show safety and reverse hindbrain herniation in myelomeningocele cases.
fromNature
2 months ago

What drugs are safe during pregnancy? There's a shocking lack of data

In 2021, amid the COVID‑19 pandemic, Kristin Wall became pregnant with her second child. Her physician told her that little was known about the COVID-19 vaccine's safety and effectiveness in pregnant people. Observational data - collected from those vaccinated before they knew that they were pregnant - suggested that the vaccine was safe, so she could have it. Still, she'd have to weigh up the risks and benefits herself.
Public health
fromwww.theguardian.com
1 month ago

Giving stem cells in utero to babies with spina bifida boosts quality of life, trial finds

A trial in the US found that applying stem cells from the mother's placenta to her baby's spine while it was being repaired was safe and improved the child's mobility and quality of life. Dr Diana Farmer, who led the study, said it was conceivable that the experimental therapy could become the usual way that spina bifida is treated before babies are born.
Medicine
Public health
fromAxios
1 month ago

More pregnant Americans are skipping prenatal care, CDC finds

First-trimester prenatal care in the U.S. declined to 75.5% in 2024, with late or no care increasing to 7.3% nationally, affecting all age groups and most racial and ethnic populations.
Medicine
fromDaily Mom magazine
2 months ago

Micro Needling While Pregnant: Treatments Are Pregnancy Safe

Microneedling can improve skin texture and reduce scarring, but pregnancy introduces safety concerns that warrant postponement or safer alternatives.
Medicine
fromThe Atlantic
2 months ago

Their Mutated Genes Were Supposed to Be Harmless

People who carry single-gene mutations for disorders like thalassemia can experience real health effects, including lethargy and fainting, despite being labeled asymptomatic.
Medicine
fromIndependent
1 month ago

Newborns to be screened for two more conditions as part of 'heel prick' test this year

Newborn screening programs are expanding to include testing for SCID and SMA, with equipment installed and roll-out testing beginning this year.
Medicine
fromNews Center
2 months ago

Evaluating Treatment of Heart Defects in Preterm Infants - News Center

Early pharmacologic closure of patent ductus arteriosus in extremely preterm infants did not improve survival compared with expectant management.
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