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Science
fromNews Center
12 hours ago

Shape-Shifting Cell Channel Reveals New Target for Precision Drugs - News Center

Pannexin-1 channels dynamically dilate and constrict to regulate passage of ions and large signaling molecules, and a malaria drug can selectively modulate this gating.
fromwww.mercurynews.com
3 months ago

UC research works on balancing act to combat cocaine addiction

One of the key elements of the new study was ensuring that treatments don't dampen the same neural responses that enable people to enjoy the positive feelings they receive from activities such as eating and exercising. Part of the reason it's so hard to treat drug addiction is because they essentially hijack brain circuits that are involved in processing natural rewards and essentially overstimulate those when these addictive drugs are ingested, said Scott Sternson, a study leader from UCSD's Department of Neurosciences.
Medicine
Health
fromNews Center
5 months ago

Novel Molecular Mechanisms Inform Targeted Therapies for Chronic Kidney Disease - News Center

Genetic mutations in the PKD2 gene cause polycystic kidney disease through defects in ion channel function.
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