#innate-immunity

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fromwww.scientificamerican.com
2 days ago

Cells Have a Death Switch That Protects Us from Viruses but Also Leads to Aging

Now researchers have discovered that a special group of about 100 immune proteins hangs out inside every cell in the body, where these proteins do nothing but wait. Then, when a virus breaks in, it seeds a crystal, and the proteins instantly clump around it, forming a scaffold for enzymes known as caspases to activate and immediately initiate cell death.
Science
Cancer
fromwww.nature.com
5 months ago

Ku limits RNA-induced innate immunity to allow Alu-expansion in primates

Ku is crucial for human cells but not essential for mouse development, suggesting an evolved function in DNA repair and immunity.
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